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Central administration of palmitoylethanolamide minimizes hyperalgesia in mice by way of inhibition of NF‐κB nuclear signalling in dorsal root ganglia. Eur J PharmacolThe exogenous administration of PEA may well in this sort of scenarios serve to replenish amounts of endogenous PEA, restoring its protecting, anti-inflammatory and analgesic resul
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"Our get the job done could for that reason set The premise for the development of a whole new class of medication with different system of action, thereby contributing to tackling the public health and fitness disaster connected to the growing misuse of and addiction to opioid prescription drugs," claims Dr. Ojas Namjoshi, co-corresponding author